Acs Medicinal Chemistry Letters

ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry. The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules. Specific areas include but are not limited to:

Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics)

Biological characterization of new molecular entities in the context of drug discovery

Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc.

Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry

Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources

Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response

Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic

Mechanistic drug metabolism and regulation of metabolic enzyme gene expression

Chemistry patents relevant to the medicinal chemistry field.

ACS 药物化学快报欢迎收录讨论药物化学各个方面的稿件。该期刊将发表涉及广泛主题的研究，包括化合物设计和优化、生物评估、药物输送、成像剂以及小分子和大分子生物活性分子的药理学。具体领域包括但不限于：

先导生物活性分子和药物（小分子和生物制剂）的鉴定、合成和优化

药物发现背景下新分子实体的生物学表征

用于鉴定或 SAR 分析生物活性分子、配体及其靶标等的计算、化学信息学和结构研究。

新颖和改进的方法，包括辐射生物化学，广泛应用于药物化学

从合成和天然（植物和其他）来源发现生物活性分子的技术

解决药物处置和反应机制的药代动力学/药效学研究

用于增强药物设计和将药物化学转化为临床的药物遗传学和药物基因组学研究

药物代谢机制和代谢酶基因的调控表达

与药物化学领域相关的化学专利。

该刊已被国际权威数据库SCIE收录，该刊致力于发表经过严格同行评审的高质量原创文章，反映CHEMISTRY, MEDICINAL领域的新进展、新技术、新成果，促进该领域科研交流和科研成果转化。该刊2023年影响因子为3.5，平均审稿速度为 一般,3-8周 ，近四年来没有被列入预警名单。如果您需要投稿发表服务及指导，可以联系我们的客服老师，我们专业专注服务期刊投稿协助10年，为您提供期刊投稿个性化定制服务，并且我们确保严格保密您的个人信息及稿件内容。