Acs Synthetic Biology

The journal is particularly interested in studies on the design and synthesis of new genetic circuits and gene products; computational methods in the design of systems; and integrative applied approaches to understanding disease and metabolism.

Topics may include, but are not limited to:

Design and optimization of genetic systems

Genetic circuit design and their principles for their organization into programs

Computational methods to aid the design of genetic systems

Experimental methods to quantify genetic parts, circuits, and metabolic fluxes

Genetic parts libraries: their creation, analysis, and ontological representation

Protein engineering including computational design

Metabolic engineering and cellular manufacturing, including biomass conversion

Natural product access, engineering, and production

Creative and innovative applications of cellular programming

Medical applications, tissue engineering, and the programming of therapeutic cells

Minimal cell design and construction

Genomics and genome replacement strategies

Viral engineering

Automated and robotic assembly platforms for synthetic biology

DNA synthesis methodologies

Metagenomics and synthetic metagenomic analysis

Bioinformatics applied to gene discovery, chemoinformatics, and pathway construction

Gene optimization

Methods for genome-scale measurements of transcription and metabolomics

Systems biology and methods to integrate multiple data sources

in vitro and cell-free synthetic biology and molecular programming

Nucleic acid engineering.

该期刊特别关注新基因电路和基因产品的设计和合成研究；系统设计中的计算方法；以及理解疾病和新陈代谢的综合应用方法。

主题可能包括但不限于：

遗传系统的设计和优化

遗传电路设计及其组织成程序的原理

辅助遗传系统设计的计算方法

量化遗传部件、电路和代谢通量的实验方法

遗传部件库：它们的创建、分析和本体表示

蛋白质工程，包括计算设计

代谢工程和细胞制造，包括生物质转化

天然产物获取、工程和生产

细胞编程的创造性和创新性应用

医疗应用、组织工程和治疗细胞的编程

最小细胞设计和构建

基因组学和基因组替换策略

病毒工程

合成生物学的自动化和机器人组装平台

DNA合成方法

宏基因组学和合成宏基因组学分析

生物信息学应用于基因发现、化学信息学和通路构建

基因优化

转录和代谢组学的基因组规模测量方法

系统生物学和整合多种数据源的方法

体外和无细胞合成生物学和分子编程

核酸工程。

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