Oncoimmunology SCIESCI

Tumor immunology deals with the natural or therapy-induced recognition of cancers, as well as with the intricate interplay between oncogenesis, inflammation and immunosurveillance. We now create a new, high-profile journal, OncoImmunology, that specifically deals with tumor immunology. Recent progress has allowed for the first clinical demonstration (and FDA approval) of anticancer immunotherapies. There is also an ever growing suspicion that - unexpectedly - many of the currently used chemotherapeutic agents depend in their efficacy on the active contribution of immune effectors. To use a drastic metaphor, oncologists who applied successful chemotherapeutic (or radiotherapeutic) regimens have taken advantage of the immune system's capacity to recognize tumor-specific or tumor-associated antigens and to control cancer (stem) cell growth, without being aware of the invisible helping hands. As a result, immunological biomarkers are becoming ever more important to determine the prognosis of cancers and to predict the efficacy of chemotherapies. There is also a strong rationale in favor of combining conventional anticancer therapies with immunotherapies.

OncoImmunology will accept high-profile submissions in the fundamental, translational and clinical areas of tumor immunology. Submissions dealing with solid or hematological cancers, inflammation, innate and acquired immune responses will be welcome.

肿瘤免疫学处理癌症的自然识别或治疗诱导的识别，以及肿瘤发生、炎症和免疫监视之间错综复杂的相互作用。我们现在创建了一个新的、备受瞩目的期刊 OncoImmunology，专门研究肿瘤免疫学。最近的进展使得抗癌免疫疗法的首次临床证明（和 FDA 批准）成为可能。也有越来越多的怀疑——出乎意料地——许多目前使用的化学治疗剂的功效取决于免疫效应器的积极贡献。用一个激烈的比喻，成功应用化疗（或放疗）方案的肿瘤学家利用免疫系统识别肿瘤特异性或肿瘤相关抗原并控制癌症（干）细胞生长的能力，而没有意识到看不见的伸出援助之手。因此，免疫生物标志物对于确定癌症的预后和预测化疗的疗效变得越来越重要。将传统的抗癌疗法与免疫疗法相结合也有充分的理由。

OncoImmunology 将接受肿瘤免疫学基础、转化和临床领域的高调提交。欢迎提交涉及实体或血液癌症、炎症、先天性和获得性免疫反应的投稿。

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